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An ultra-high performance liquid chromatography tandem mass spectrometry method was developed and validated for the sensitive determination and unambiguous confirmation of residues of per and polyfluorinated alkyl substances PFAS in breastmilk, retail milk and infant formulas following two sample preparation methods.

The method displayed good linearity with R2 ranging from 0. Nicolas Olea. Jennifer Keller , Craig Butt. International Journal of Hygiene and Environmental Health. Elena Dellatte. Per- and polyfluorinated alkyl substances PFASs are ubiquitous environmental contaminants, present in the environment and in the human body.

They have raised global concern because of their diffusion in the environment, particularly in water, causing cases of human overexposure due to consumption of contaminated drinking water. Human biomonitoring is the most effective way to characterize human exposure to PFASs, and it is important that as many labs as possible could easily perform this kind of analysis. Analytical methods for quantitation of PFAS mixtures in human serum have been developed, but most of them required materials that are not always easily available in all the laboratories.

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