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A retrospective study of cases of colorectal cancer collected at the epidemiology department of the University Hospital Center UHC of Tlemcen between January and December was performed. The epidemiological profile has shown that colorectal cancer in our region ranks 3 rd in both sexes. There were men A predominance of males is noted in age group, while for the female sex, the dominance is between years old. A significantly higher rate was recorded for rectal cancer Variable rates were recorded during the 5 years with a peak in Regular analysis of these data, if supplemented with additional data on diagnostic modalities like circular RNA diagnostic, will contribute to the assessment of the impact over time of public policies on nationally organized CRC screening.

Colorectal cancer CRC is a major public health concern around the world. It is the third most common malignant neoplasm in the world and the second most common cause of cancer death, with an estimated , deaths in ; of which The term colorectal cancer refers to a slow-growing cancer that begins as a tumor or tissue growth on the inner wall of the rectum or the colon.

If this abnormal growth, called a polyp, ends up becoming cancerous, it can form a tumor on the wall rectum or colon and subsequently develop into blood or lymphatic vessels, increasing the risk of metastasis to other anatomical sites 2 - 3.