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Apoptotic stress causes mtDNA release during senescence and drives the SASP

Gerontology 1 January ; 55 1 : — All somatic cells are subject to aging. Germline links generations, and thus, pluripotent germ cells are considered potentially immortal. The current understanding how the germline escapes this otherwise inevitable phenomenon is outlined in this article.

Sign In or Create an Account. Search Dropdown Menu. Advanced Search. Skip Nav Destination Close navigation menu Article navigation. Volume 55, Issue 1. Article Navigation. Research Articles November 13 This Site. Google Scholar. Gerontology 55 1 : — Article history Received:. Cite Icon Cite. This content is only available via PDF. Karger AG, Basel. Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.

Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication.

However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions.

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