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During perimenopause , progesterone levels decline along with estrogen. A low progesterone-to-estrogen imbalance — known as estrogen dominance — can lead to symptoms ranging from weight gain to adult acne , plus many mood-related symptoms. Estrogen often gets the starring role when we talk about menopause symptoms and other hormonal issues. Is your progesterone ratio too low and in a state of imbalance? Common signs of low progesterone in perimenopause include:. Progesterone is the main hormone responsible for regulating your cycle.
Typical menstrual cycles are about 28 days long. If your cycle is much longer, much shorter or just unpredictable then this could be due to low progesterone. If you are eating well and exercising, but have hormonal imbalance — including low progesterone — your body can go into weight gain mode no matter what you do. Progesterone interacts with your neurotransmitters, particularly GABA. When progesterone is low you may have symptoms of depression, anxiety, irritability and insomnia which can get even worse before your cycle.
Research shows that certain PMS symptoms — specifically mood-related ones like irritability, anxiety, fatigue, insomnia and even tearfulness — are tightly linked to low progesterone levels during that second half of the menstrual cycle, known as the luteal phase.
One study notes that women with higher progesterone levels during this phase of their cycle have much less irritability and fatigue. Studies have shown that progesterone helps to regulate the production of DHT and is a key to keeping it under control. When progesterone falls out of ratio with estrogen in perimenopause, the imbalance can contribute to vaginal dryness, vaginal atrophy a loss of muscle tension and decreased clitoral sensitivity.
