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Share sensitive information only on official, secure websites. Martin, MSc 1 ; J. Lindsey, MS 1 View author affiliations. Symptomatic persons usually develop an acute systemic febrile illness. Description of System: WNV disease is a nationally notifiable condition with standard surveillance case definitions. Variables collected include patient age, sex, race, ethnicity, county and state of residence, date of illness onset, clinical syndrome, hospitalization, and death.
Neuroinvasive disease incidence and case-fatalities increased with increasing age, with the highest incidence 1. The national incidence of WNV neuroinvasive disease peaked in 0. Although national incidence was relatively stable during — average annual incidence: 0. During —, the highest average annual incidence of neuroinvasive disease occurred in North Dakota 3. Interpretation: Despite the recent stability in annual national incidence of neuroinvasive disease, peaks in activity were reported in different years for different regions of the country.
Variations in vectors, avian amplifying hosts, human activity, and environmental factors make it difficult to predict future WNV disease incidence and outbreak locations.
Public Health Action: WNV disease surveillance is important for detecting and monitoring seasonal epidemics and for identifying persons at increased risk for severe disease.
