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Prevention strategies have been applied since then. Early diagnosis and technologies, such as the use of ECMO Extracorporeal Membrane Oxygenation and Hantavirus immune plasma, have contributed to increasing the survival of people due to this disease at the national level.

This knowledge contributes to substantiating and justifies the need to invest in technology and reinforce interventions related to the early diagnosis and prevention of this disease in the region. The most affected population is young men, residents in rural areas, and mainly from a low socioeconomic segment. The regional profile of Hantavirus cases makes it possible to identify three communes with the highest number of cases: El Carmen, Coihueco, and San Carlos.

Keywords: Andes virus; Hantavirus cardiopulmonary syndrome; Oligorizomys longicaudatus long-tailed mouse. Hantavirus is a viral disease considered an emerging zoonosis whose main vectors are wild rodents. Around 40 variants carried by different species of rodents that can transmit it to humans have been identified globally Jonsson et al.

Among rodents, there is horizontal transmission, not producing the disease in them Pavletic, The circulating virus in Chile is the Andes variant, which is transmitted by the wild rodent Oligoryzomys longicaudatus long-tailed mouse , a protected species in Chile Padula et al. The long-tailed mouse transmits the virus to humans mainly through inhalation of aerosols produced from the urine and feces of infected rodents. Other forms of transmission have been described besides mucosal nasal, buccal, or conjunctival inoculation due to contact with virus-contaminated hands Schmaljohn and Hjelle, Person-to-person transmission has also been documented, corresponding to a low-frequency situation in which the mode of contagion is not clear Padula et al.

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