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June 15, , by Linda Wang. New cases of colorectal cancer in people under the age of 50 have been rising at an alarming rate over the past several decades. Now, a study has identified four warning signs that, according to the investigators, could help encourage younger adults to seek medical care so they can potentially catch the disease at an earlier and more treatable stage. To conduct the study, the research team analyzed insurance claims data on more than 5, people diagnosed before age 50, called early-onset colorectal cancer, and more than 22, people without cancer controls.
The analysis showed that, in the period of 3 months to 2 years before people with colorectal cancer were diagnosed, four signs were more commonly reported in people who developed colorectal cancer than in matched controls:. Having just one of these signs during this period was associated with nearly twice the likelihood of being diagnosed with early-onset colorectal cancer as having none of the signs.
Having three or more of these signs was associated with six times the likelihood of being diagnosed with the disease. Clinicians also need to be aware of these signs, Dr. Colorectal cancer is the third most common cancer in the United States among both men and women. The widespread adoption of screening in the mids has led to a steady decline in cases of colorectal cancer among adults aged 50 and older. However, new cases of early-onset colorectal cancer, while still relatively rare, have been rising since the mids.
In response to this trend, cancer screening guidelines now recommend people start getting screened for colorectal cancer at age 45 instead of But half of early-onset colorectal cancers are diagnosed in people under 45 years old, for whom screening is not routinely recommended except for those with inherited mutations in specific cancer-related genes , such as people with Lynch syndrome , or with a first-degree relative who has had colorectal cancer.
