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You have full access to this open access article. Rh-GIOP is a cohort study designed to evaluate bone health in patients with inflammatory rheumatic diseases. This cross-sectional analysis assessed the baseline visits of all patients with PMR or any kind of vasculitis. Following univariable analysis, multivariable linear regression analysis was performed.

The lowest T-score of either the lumbar spine or the femur was chosen as the dependent variable to examine the relationship between MTX use and BMD.

These analyses were adjusted for a variety of potential confounders, including age, sex, and glucocorticoid GC intake. The remaining patients had the following diseases: PMR The mean age was It is not associated with BMD levels. Patients with polymyalgia rheumatica PMR and vasculitides are at an increased risk of osteoporosis OP and fragility fractures [ 1 , 2 ].

The underlying causes have not been fully identified yet as recent studies challenge the old assumption that glucocorticoids GCs are the main culprits. As it is well-known that inflammation increases the risk of fracture and deteriorates bone health, [ 4 , 5 , 6 , 7 ], we also assessed CRP but found no evidence for an association between CRP and bone density.