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Federal government websites often end in. The site is secure. Preview improvements coming to the PMC website in October Learn More or Try it out now. Vitamin K antagonists, such as warfarin, have a narrow therapeutic window; patients on these therapies therefore require regular international normalized ratio INR monitoring to maintain optimal dosing. This involves periodic checks and laboratory testing using venepuncture, which are often perceived as a burden. This study aimed to determine the accuracy and precision of the LumiraDx INR Test, a new point-of-care in vitro diagnostic platform, in an anticoagulation clinic setting.
In addition, feedback was collected from health-care professionals via a self-completed questionnaire. This trial was registered at ClinicalTrials. Feedback from health-care professionals indicated that the instructions given by the system were easy to follow. Vitamin K antagonists VKA oral anticoagulation therapies, such as warfarin, have been used in primary and secondary care for more than 60 years, and both the short-term and long-term effects in patients have been well established.
There are multiple factors that can affect INR control, such as vitamin K supplementation, drug interactions, and alcohol consumption. The LumiraDx Platform is a POC system designed for the measurement of multiple parameters near the patient using small volume blood sampling methods, such as capillary blood from fingersticks.
The objective of this study was to evaluate the accuracy and precision of the new LumiraDx Platform INR Test in a POC setting using both direct application and pipette transfer of capillary blood to the test strips for potential inclusion in future routine clinical practice.