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Animal welfare, ecological sustainability, and controlled usage of medical pharmaceuticals are all objectives for producing healthy products devoid of chemical residues or pharmaceutical drugs 1. Recently, along with implementing antibiotics bans in many countries, several studies have been conducted to search for alternatives to antibiotics in the livestock industry 2 due to increased interest in human nutrition 3.

Since ancient times, honey bee venom BV has been frequently used as a painkiller and treatment for inflammatory diseases Yoon et al. Son et al. In several investigations, bee venom has been established to have anti-inflammatory and antibacterial characteristics.

Pucca et al. In addition, the BV contains biologically active amines, such as histamine, adrenaline, and non-peptide derivatives, with a range of pharmacological properties. Melittin, apamin, and adolapin polypeptides act as anti-inflammatory and antibacterial factors and are the primary elements of BV 7.

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