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To browse Academia. Yasser Fouad. HR and Amin HE did the endoscopic procedures; Tawfik HM performed the pathology experiments; Ghany WA coordinated and provided the collection of the human material; Fouad YM designed the study and wrote the manuscript; All authors cooperated in the analysis of the results and final revision of the manuscript.

Enzo Ierardi. Helicobacter pylori H. The aim of this editorial is to report on the recent information about the mechanisms accounting for the resistance to the different antibiotics currently utilized in H. Different mechanisms of resistance to clarithromycin, metronidazole, quinolones, amoxicillin and tetracycline are accurately detailed point mutations, redox intracellular potential, pump efflux systems, membrane permeability on the basis of the most recent data available from the literature.

The next hope for the future is that by improving the knowledge of resistance mechanisms, the elaboration of rational and efficacious associations for the treatment of the infection will be possible. Another auspicious progress might be the possibility of a cheap, feasible and reliable laboratory test to predict the outcome of a therapeutic scheme. Giuseppina Liguori. Jin Lee. Carlo Calabrese. To elucidate cell proliferation in erosive reflux disease ERD and non-erosive reflux disease NERD , we evaluated markers in squamous epithelial cells.

Thirty-four consecutive patients with gastroesophageal-reflux-disease-related symptoms 21 NERD and 13 ERD were evaluated for the enrolment into the study. All patients underwent h pH monitoring, standard endoscopy, and biopsy for histological evaluation. The expression of cyclins D and A was evaluated by real-time reverse transcription polymerase chain reaction RT-PCR from isolated epithelial cells.