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Access provided by Shenyang Normal University. Young men who have sex with men YMSM under 25 years old are among the few populations with increasing numbers of new HIV infections in parts of the world where HIV incidence is declining overall. Results were stratified according to study population sampling method used probability and non-probability based. Forty-seven studies from 17 countries were published in the last 10 years.

HIV prevalence tended to increase over time in studies sampling at different time points. While the HIV prevalence in the adult general population is 0. Despite the emergence of new HIV prevention technologies and strategies such as treatment as prevention TasP, endorsed by World Health Organization [WHO] in , pre-exposure prophylaxis PrEP, recommended by WHO since , and HIV self-testing recommended by WHO since [ 9 ], the number of new infections has decreased only slightly over the last decade and is on the rise among young key populations [ 2 ].

The overall number of people on PrEP across the region remains insufficient to have a significant impact on the epidemic. Lack of access to appropriate sexual education and preventive strategies, condomless and PrEP-less sex, use of alcohol and drugs during sex, transactional sex, and low perceived HIV risk are some of the factors associated with higher vulnerability to HIV among YMSM [ 11 , 16 , 17 , 18 , 19 ].

Homophobia, stigma, and fear of disclosing sexual orientation are other barriers YMSM face in accessing prevention and care services, as well as participation in research [ 22 , 23 , 24 ]. An important data challenge identified in LAC to date has been utilization of methods that produce representative samples of hidden and hard-to-reach populations in research on key populations like YMSM.