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Alberto Zaniboni. Background: In clinical trials, the assessment of safety is traditionally focused on the overall rate of high-grade and serious adverse events AEs. A new approach to AEs evaluation, taking into account chronic low-grade AEs, single patient's perspective, and timerelated information, such as ToxT analysis, should be considered especially for less intense but potentially long-lasting treatments, such as maintenance strategies in metastatic colorectal cancer mCRC.
Conclusions: Most of chemotherapy-related AEs except for HFS and neuropathy reach the highest level in the first cycles, then decrease, probably due to their active clinical management. Log in with Facebook Log in with Google. Remember me on this computer. Enter the email address you signed up with and we'll email you a reset link. Need an account? Click here to sign up.
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