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How COVID-19 affects mitochondrial disease patients

This page has been archived and is no longer updated. What variety is there in mitochondria? Mitochondria occur in various forms across various eukaryotic groups, yet considerations on the origin of mitochondria sometimes neglect this understanding.

Four main mitochondrial types can be distinguished on the basis of functional criteria concerning how or whether ATP is produced. These functional types do not correspond to natural groups, because they occur in an interleaved manner across the tree of eukaryotic life. Instead they correspond to ecological specializations. Trachipleistophora and Cryptosporidium mitosomes denotes that these organisms are not anaerobes in the sense that they do not inhabit O 2 -poor niches, but that their ATP supply is apparently O 2 -independent.

A Schematic summary of salient biochemical functions in mitochondria, including some anaerobic forms. B Schematic summary of salient biochemical functions in hydrogenosomes. C Schematic summary of available findings for mitosomes and 'remnant' mitochondria.

The asterisk next to the Trachipleistophora and Cryptosporidium mitosomes denotes that these organisms are not anaerobes in the sense that they do not inhabit O 2 -poor niches, but that their ATP supply is apparently O 2 -independent. Eukaryotic evolution, changes and challenges. Nature , — All rights reserved. The double membranes that enclose the organelles are depicted as rectangles with rounded corners.

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