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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Competing interests: The authors have declared that no competing interests exist. Peter J. The neglected tropical diseases NTDs are the most common infections of the world's poorest people living in developing countries [1] — [7].
They are mostly comprised of chronic parasitic and related infections, with the most common NTDs represented by the soil-transmitted helminthiases, schistosomiasis, lymphatic filariasis, onchocerciasis, and trachoma [1].
Among their common features, the NTDs result in prolonged periods of disability and actually help to promote poverty through their long-standing effects on child development and worker productivity [2]. It is not commonly appreciated that the NTDs are widespread throughout Central Asia where they are also a major determinant of poverty [8]. The five mostly landlocked Central Asian countries—Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan, and Uzbekistan Figure 1 —were established upon the breakup of the former Soviet Union in The five nations have a combined population of 60 million people, with three of them—Kyrgyzstan, Tajikstan, and Uzbekistan—exhibiting a Human Development Index HDI that is ranked below , whichis more or less equivalent to nations such as Guatemala, India, Indonesia, and South Africa [10].
During the Soviet era in the 20th century, some gains were made in parasite and NTD control. For instance, in Uzbekistan a number of NTDs were either eradicated or eliminated as a public health problem, including dracunculiasis in , urban cutaneous leishmaniasis in , malaria in , visceral leishmaniasis in , and hookworm infection in [11].