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Thank you for visiting nature. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer.
In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Less than half of patients with chronic diseases, including multiple sclerosis MS , adhere to their prescribed medications. Treatment selection is essential for patient adherence.
The aim of this study was to explore the potential factors influencing nonadherence to disease-modifying therapies DMTs in MS. This prospective, cross-sectional study was performed at the Multiple Sclerosis Center between and In total, 85 patients were eligible for final analysis. Forty-one patient Male sex, oral administration of drugs, and longer treatment duration were associated with nonadherence. Patients with a higher score on the Symbol Digit Modalities Test, who were receiving self-injection therapy, had shorter treatment duration, and higher disability, were more likely to be adherent to DMT than those without.
Treatment options for multiple sclerosis MS have greatly expanded recently 1 , 2. Improving disease stability and quality of life in patients with chronic diseases requires prolonged and often lifelong medication. Less than half of patients with chronic diseases and MS adhere to their prescribed medications, which precludes the full benefit of treatment, worsens disease outcomes, and accelerates disease progression 3 , 4 , 5. MS is one of the diseases that, despite the coming of new and short treatment options 1 , 2 , still requires frequent parenteral or oral administration of disease-modifying therapy DMT daily or a few times a week for an undefined extended period.