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Liver transplant recipients have an increased risk of pulmonary infections, but little is known about the burden of chronic pulmonary diseases in this group. We aimed to assess the prevalence of elevated F E NO 50 in liver transplant recipients and compare it to controls from the general population.

The analyses were adjusted for known and suspected confounders. Conclusion: The liver transplant recipients had elevated F E NO 50 , implying increased eosinophilic airway inflammation. The clinical impact of this finding needs further investigation. End-stage liver disease is associated with pulmonary complications, including hepatopulmonary syndrome and portopulmonary hypertension 1 , 2. Furthermore, in experimental animal models, liver injury has been shown to cause pulmonary inflammation and tissue damage 3 , 4.

Liver transplantation is a lifesaving treatment for patients with end-stage liver disease, but pulmonary complications may occur post-transplantation.

Thus, liver transplant recipients have an increased risk of pulmonary infections, which can result in long-lasting pulmonary injury that may dispose them to common chronic pulmonary diseases such as chronic obstructive pulmonary disease COPD and asthma 5 , 6. In addition, liver transplant recipients have an increased risk of drug-induced pulmonary disease due to immunosuppressive medication 7 — 9.