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Objective: The prevalence of syphilis differs considerably between different populations and indi-vidual level risk factors such as number of sex partners seem unable to completely explain these differences. The effect of network level factors, such as the prevalence of partner concurrency, on syphilis prevalence has not hitherto been investigated. Study design: Linear regression was per-formed to assess the relationship between the prevalence of male concurrency and prevalence of syphilis in each of 11 countries for which we could obtain comparable data.

Syphilis prevalence rates were obtained from antenatal syphilis serology surveys done in the same countries. In addition, we used linear regression to assess if there was a relationship between syphilis and concurrency prevalence of various racial and ethnic groups within the United States and South Africa.

Conclusions: The findings of an ecological-level association between syphilis and partner concurrency need to be replicated but suggest that efforts directed towards decreasing partner concurrency may reduce syphilis prevalence. Why do some ethnic groups have a prevalence of syphilis of up to five times greater than others within the same location and why does syphilis prevalence vary by an even greater degree between countries [1] -[4]?

Syphilis is a sexually transmitted infection STI caused by infection with Treponema pallidum subspecies pallidum. STIs are transmitted over networks of sexual partnerships, and hence the structure of these networks will influence how quickly and extensively STIs will spread.