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Federal government websites often end in. The site is secure. Preview improvements coming to the PMC website in October Learn More or Try it out now. Table S2. No significant differences appeared in mortality for pravastatin vs usual care hazard ratio [ HR ], 0.

These findings are consistent with evidence from other large trials that show statins prevent CHD and add evidence that they are effective for CHD prevention in black patients.

Further, we will examine whether differences emerge for outcomes that were not statistically different at the trial's end. Total cholesterol TC was measured at baseline and at the year 2, 4, and 6 visits. Consistent with the original trial, total mortality was the primary outcome for the LLT extension study. A death identified through the NDI or SSA was verified at the Coordinating Center after receipt of a death certificate from the state, Commonwealth, or other jurisdictions.

Death certificates were used for verification of decedent identity only. To compare baseline characteristics of participants assigned to UC and pravastatin, contingency table and z tests were used. Intermediate outcomes of drug adherence and laboratory measures at baseline, year 2, year 4, year 6, and end of trial were examined. Evaluations of the effect of assigned treatment on risk for primary and secondary outcomes were performed using Cox regression.